Ribosomal protein L14



Ribosomal protein L14 (RPL14) is one of the 34 proteins which belong to the large 50S subunit of the prokaryotic ribosome or to the ca. 49 proteins in the large 60S subunit of the eukaryotic ribosome. The images at the left and at the right correspond to one representative RPL14, i.e. the crystal structure of Ribosomal protein L14 from Geobacillus stearothermophilus (1whi).

RPL14
2kds, 2joy – RPL14 – Sulfolobus solfataricus – NMR

1whi – RPL14 – Geobacillus stearothermophilus

L14 in 50S subunit+RNA
2xg0, 2xg2, 3kir, 3kit, 3kiw, 3kiy – TtRPL14 in 50S subunit+RNA fragments - Thermus thermophilus

2x9s, 2x9u, 3kni, 3knk, 3knm, 3kno, 2wrj, 2wrl, 2wro, 2wrr, 3hux, 3huz, 2wh2, 2wh4, 2wdi, 2wdj, 2wdl, 2wdn, 1vsp, 2v47, 2v49, 1vsa, 2hgj, 2hgq, 2hgu, 2j01, 2j03, 1yl3, 3mrz, 3ms1, 3i8f, 3i8i, 3i9c, 3i9e, 3f1f, 3f1h, 3d5b, 3d5d, 2b66, 2b9n, 2b9p, 1giy - TtRPL14 in 50S subunit+5S RRNA+23S RRNA

3fin - TtRPL13 in 50S subunit+5S RRNA+23S RRNA – Cryo-EM

2wwq – EcRPL13 in 50S subunit+5S RRNA+23S RRNA+mRNA+P-site tRNA – Escherichia coli

3i1n, 3i1p, 3i1r, 3i1t, 3i20, 3i22, 3e1b, 3e1d, 3df2, 3df4, 2vhn, 2qov, 2qox, 2i2t, 2i2v, 1vs6, 1vs8, 2aw4, 2awb - EcRPL14 in 50S subunit+5S RRNA+23S RRNA

3fik, 2gya, 2gyc, 3bbx, 1p85, 1p86 - EcRPL14 in 50S subunit+5S RRNA+23S RRNA – Cryo-EM

3kcr - EcRPL14 in 50S subunit+5S RRNA+23S RRNA+preprotein translocase

3bbo - RPL13 in 50S subunit+5S RRNA+23S RRNA+4.8S RRNA – Cryo-EM – spinach

2zjq, 2zjr - DrRPL14 in 50S subunit+5S RRNA+23S RRNA – Deinococcus radiodurans

1kqs, 1qvg - HmRPL14P in 50S subunit+5S RRNA+23S RRNA+CCA - Haloarcula marismortui

1jj2, 1ffk, 3cc2, 2qa4, 1s72 - HmRPL14P in 50S subunit+5S RRNA+23S RRNA

3cc7, 3cce, 3ccj, 3ccl, 3ccm, 3ccq, 3ccr, 3ccs, 3ccu, 3ccv - HmRPL14P in 50S subunit+5S RRNA+23S RRNA (mutant)

1yj9 - HmRPL14P in 50S subunit (L22 mutant)+5S RRNA+23S RRNA

1vq4, 1vq5, 1vq7, 1vql, 1vqm, 1vqp - HmRPL14P in 50S subunit+5S RRNA+23S RRNA+transition state analog

1vq6, 1vqk, 1vqn - HmRPL14P in 50S subunit+5S RRNA+23S RRNA+ c-hpmn+CCA-Phe-caproic acid-biotin

1q86 - HmRPL14P in 50S subunit+5S RRNA+23S RRNA+CCA-Phe-caproic acid-biotin

1vqo - HmRPL14P in 50S subunit+5S RRNA+23S RRNA+ CCPMN

1qvf - HmRPL14P in 50S subunit+5S RRNA+23S RRNA + deacylated tRNA minihelix

3iy9 – RPL14 in 50S subunit – Leishmania taretolae

L14 in 50S subunit + antibiotics
3cxc – RPL14 in 50S subunit+5S RRNA+23S RRNA +oxazolidinone inhibitor – Halobacterium marismortui

3dll - DrRPL14 in 50S subunit+5S RRNA+23S RRNA+general stress protein Ctc+oxazolidinone inhibitor

2zjp - DrRPL14 in 50S subunit+5S RRNA+23S RRNA+general stress protein Ctc+nosiheptide

3cf5 - DrRPL14 in 50S subunit+5S RRNA+23S RRNA+general stress protein Ctc+thiostrepton

1xbp - DrRPL14 in 50S subunit+5S RRNA+23S RRNA+general stress protein Ctc+thiamulin

1sm1 - DrRPL14 in 50S subunit+5S RRNA+23S RRNA+general stress protein Ctc+quinupristin+dalfopristin

1nwx - DrRPL14 in 50S subunit+5S RRNA+23S RRNA+general stress protein Ctc+ABT-773

1nwy - DrRPL14 in 50S subunit+5S RRNA+23S RRNA+general stress protein Ctc+azithromycin

2qam, 2qao, 2qoz, 2qp1 - EcRPL14 in 50S subunit+5S RRNA+23S RRNA+neomycin

2qba, 2qbc - EcRPL14 in 50S subunit+5S RRNA+23S RRNA+gentamicin

1k73, 1kc8, 1k8a, 1k9m, 1kd1, 1m1k, 3i55, 3i56, 3g4s, 3g6e, 3g71, 2qex, 3cc4, 3cd6, 2otj, 2otl, 1yit, 1q7y, 1q81, 1q82, 1n8r, 1nji - HmRPL13P in 50S subunit+5S RRNA+23S RRNA+antibiotic

1yhq, 1yi2, 1yij, 1yjn, 1yjw - HmRPL14P in 50S subunit+5S RRNA+23S RRNA (mutant)+antibiotic

1m90, 3cma, 3cme, 1vq8, 1vq9 - HmRPL14P in 50S subunit+5S RRNA+23S RRNA+ sparsomycin+CCA-Phe-caproic acid-biotin

L14 in large + small ribosomal subunit
1ml5 - EcRPL14 in 50S ribosomal subunit+30S ribosomal subunit+THX+chain release factor 2+P-site tRNA+tRNA Phe+mRNA fragment+23S RRNA+5S RRNA+16S RRNA – EM

L14 in 50S subunit + ribosome releasing factor (RRF)
2qbe, 2qbg, 2qbi, 2qbk, 2z4l, 2z4n - EcRPL13 in 50S subunit+5S RRNA+23S RRNA+RRF

2rdo - EcRPL14 in 50S subunit+5S RRNA+23S RRNA+EF-G+RRF – Cryo-EM

L14 in 50S subunit + various proteins
2vhm - EcRPL14 in 50S subunit+5S RRNA+23S RRNA+PDF C-terminal helix

2j28 - EcRPL14 in 50S subunit+5S RRNA+23S RRNA+signal recognition particle – Cryo-EM

1vor, 1vou, 1vow, 1voy, 1vp0, 1pnu, 1pny - EcRPL13 in 50S subunit+5S RRNA+23S RRNA+general stress protein Ctc

1nkw - DrRPL14 in 50S subunit+5S RRNA+23S RRNA+general stress protein Ctc

1w2b - HmRPL14P in 50S subunit+5S RRNA+23S RRNA+trigger factor N-terminal

L14 in part of 50S subunit
1c04 – HmRPL14P+RPL2+RPL6+RPL11+23S RRNA fragment

487d – RPL14+RPL1+RPL2+RPL9+RPL11+RPL6+RPL25 – Cryo-EM